Cognition & focus

Sharper days.

Clearer thinking, calmer baseline, less brain fog. Sleep and HRV will tell you it's working.

From $290 / moPowered by The Brain Protocol · Cognitive support
What's in this protocol

What you'll be prescribed.

Why These Work Together

Cognitive performance depends on two things: the acute signaling environment in your brain (neurotransmitters, BDNF, neural connectivity) and the underlying energy infrastructure that powers it all (mitochondrial function, ATP production, cellular repair). The Brain Stack addresses both layers simultaneously.

Semax/Selank provides the immediate cognitive lift. Semax increases BDNF expression, which supports neuroplasticity — your brain's ability to form and strengthen neural connections. It modulates dopamine and serotonin systems to improve focus, motivation, and working memory. Selank calms the anxiety and mental noise that fragment attention, creating the clear, focused state needed for demanding intellectual work. The nasal spray format means effects begin within minutes.

NAD+ provides the deep infrastructure. The brain is the most energy-hungry organ in the body. Neurons fire billions of times per day, and each firing requires ATP. NAD+ is the molecule that makes ATP production possible in mitochondria. When NAD+ levels are low — which happens naturally with age, stress, and sleep deprivation — cognitive function degrades: brain fog, slower processing, difficulty concentrating, memory lapses.

The synergy is profound. Semax enhances the brain's signaling capacity (better connections, more BDNF, optimized neurotransmitters), while NAD+ ensures the brain has the energy to actually use that enhanced capacity. It's like upgrading your software (Semax/Selank) while also upgrading your hardware (NAD+). One without the other produces incomplete results.

NAD+ also activates sirtuins — longevity proteins involved in DNA repair and cellular maintenance. This means the Brain Stack doesn't just improve cognitive performance today; it supports the long-term health of your neural tissue. Neuroprotection and performance in one protocol.


Typical Results Timeline

Weeks 1–2: Semax/Selank effects are noticeable almost immediately — improved focus, reduced anxiety, clearer thinking within the first few days of use. NAD+ begins restoring cellular energy, and many patients report improved mental stamina and less afternoon brain fog. Week 4: Cognitive improvements deepen. Working memory and information retention improve. Patients report being able to sustain focus for longer periods and handling complex tasks with less mental fatigue. Mood stability improves as Selank's anxiolytic effects build. Week 8: Full cognitive optimization. Patients consistently report peak mental performance — sharper recall, faster processing, sustained energy throughout demanding work days. The combination of acute nootropic effects and deep cellular energy produces a level of cognitive function that patients describe as transformative. Week 12: Cumulative benefits are fully established. NAD+'s neuroprotective effects (sirtuin activation, DNA repair) add a longevity dimension. Patients often describe feeling like they've gained back years of cognitive capability.

Pricing

The Brain Protocol starts at $290 / month. You'll see your exact total — including medical processing and shipping — at checkout before you pay. See the live total →

What's included with every program:
  • Medical review by the prescribing clinical team
  • Patient care team access throughout your program
  • Connected health tracking (Oura, Whoop, Apple Health)
  • Member resources and educational guides
  • Two-day shipping from a licensed 503A compounding pharmacy
  • One order — no auto-renewal

If the clinical team declines your application, the full amount is refunded to your card within 5–7 business days.


How to Get Started

Step 1 — Pick your protocol. The Brain Stack is for anyone who depends on cognitive performance. Step 2 — Quick health intake. 5-minute online questionnaire. No office visit. Step 3 — Provider review. Licensed physician reviews within 24 hours. Step 4 — Delivered to your door. Nasal spray + NAD+ vial ship together with two-day shipping.
Common questions

Frequently asked.

Is the Brain Stack like taking Adderall?+
No. The Brain Stack works through entirely different mechanisms. Semax/Selank enhances BDNF and modulates GABA — it doesn't flood your system with dopamine and norepinephrine like stimulants do. NAD+ restores cellular energy rather than borrowing it. There's no jitteriness, no crash, no appetite suppression, no dependence risk, and no tolerance buildup.
Can I use the Brain Stack for studying or exams?+
Absolutely. The Brain Stack is popular with students and professionals preparing for intensive cognitive demands. Semax/Selank provides acute focus and memory enhancement, while NAD+ sustains mental energy over long study sessions. Some patients use the nasal spray strategically before exams or presentations.
Will I become dependent on the Brain Stack?+
Research and clinical use have not shown physical dependence with either compound. Semax/Selank does not produce the tolerance or withdrawal associated with stimulants or benzodiazepines. NAD+ is a naturally occurring molecule. Many patients use the Brain Stack intermittently without difficulty stopping.
How do I use the nasal spray and the injection?+
Semax/Selank is a nasal spray — 1-2 sprays per nostril, typically in the morning. NAD+ is a subcutaneous injection, typically 2-3 times per week. They work through completely different delivery methods and can be used at different times of day. Full instructions are included with your shipment.
Is the Brain Stack safe with caffeine?+
Yes. Most patients use the Brain Stack alongside their normal caffeine intake. The combination of Semax's focus enhancement, Selank's anxiety reduction, and caffeine's alertness is particularly effective. If you're caffeine-sensitive, monitor your response and adjust.
Can I add other peptides to the Brain Stack?+
Yes. Some patients add GHK-Cu for neuroprotective benefits, or Glutathione for antioxidant support. Your Uplevel Bio provider can help customize the protocol to your goals. ---
Learn more

The science behind it.

Related

Other outcomes.

Begin where you are.

Five minutes to start. A real team and your data for the rest.

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